Pulmonary/Critical Care Curriculum 

Pulmonary Curriculum

Critical Care Curriculum

Community Acquired Pneumonia

Does this patient have CAP? Diagnosing pneumonia by history and physical examination. JAMA 1997;278:1440-5

Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial. JAMA 2009;302:1059-66.


An empiric integrative approach to the management of cough: ACCP evidence-based clinical practice guidelines. Chest. 2006; 129(1 Suppl):222S-231S

Controversies in the evaluation and management of chronic cough. Am J Respir Crit Care Med 2011;183:708-15. This helpful review focuses on some of the more frustrating clinical questions regarding the persistent chronic cough

Chronic Obstructive Pulmonary Disease

Global Strategy for Diagnosis, Management, and Prevention of COPD. 2017

The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. (INSPIRE Trial) Am J Respir Crit Care Med 2008; 177:19-26

Effect of systemic glucocorticoids on exacerbations of COPD. N Engl J Med 1999;340:1941-7

Interstitial Lung Disease

American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2002;165:277-304

Treatment of sarcoidosis. Clin Chest Med 2008; 29:533-48

Lung Cancer

The IASLC lung cancer staging project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2007; 2:706-14

Evaluation of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition). Chest. 2007;132(3 Suppl):108S-130S

Guidelines for management of small pulmonary nodules detected on CT scans: A statement from the Fleischner Society. Radiology 2005; 237:395-400

Pleural Disease

Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med 1972;77:507-13

Pulmonary Embolism

PIOPED Investigators. Value of the ventilation / perfusion scans in pulmonary embolism: results of the PIOPED. JAMA 1990;263:2753-9

Computed tomographic pulmonary angiography vs. ventilation-perfusion lung scanning in patients with suspected pulmonary embolism. JAMA 2007; 298:2743-53

Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism. N Engl J Med 2003; 348:1425-34

Pulmonary Hypertension

Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 2009; 179:615-21

A comparison of continuous intravenous epoprostenol (prostacyclin) and conventional therapy for primary pulmonary hypertension. N Engl J Med 1996;334:296-301

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomized placebo-controlled study. Lancet 2001; 358:1119-23

Mechanical Vents and Weaning

A comparison of four methods of weaning patients from mechanical ventilation. N Engl J Med 1995; 332:345-50

A prospective study of indexes predicting the outcome of trials of weaning from mechanical ventilation. N Engl J Med 1991; 324:1445-50

Effect of Pressure Support vs Unassisted Breathing Through a Tracheostomy Collar on Weaning Duration in Patients Requiring Prolonged Mechanical Ventilation: A Randomized Trial. JAMA. 2013 Jan 22:1-7. doi: 10.1001/jama.2013.159.

Critical Care Curriculum


ARDS NET. NIH NHLBI ARDS Mechanical Ventilation Protocol Summary

Central Line Associated Blood Stream Infections

An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU. NEJM 2006. 6;355:2725-32

Diabetes Mellitus

Evidence-based management of hyperglycemic emergencies. Diabetes Research and Clinical Practice 2011

NICE-Sugar. Intensive versus Conventional Glucose Control in Critically Ill Patients. NEJM 2009 

Hypoxic Respiratory Failure

High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure. N Engl J Med 2015;372:2185-96. DOI: 10.1056/NEJMoa1503326

Pain Management

Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit. Critical Care Medicine DOI: 10.1097/CCM.0b013e3182783b72

Physical Therapy

Early physical and occupational therapy in mechanically vented. Lancet Vol 373 2009

Renal Replacement

Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit. NEJM 2016;375:122-33. DOI: 10.1056/NEJMoa1603017


Sepsis 3: Updated expert consensus definition and diagnostic criteria. JAMA. 2016;315(8):762-774. doi:10.1001/jama.2016.0288


Spontaneous Breathing Trials

Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008; 371: 126–34

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